446-72-0 | Genistein

Chemical type

• Isoflavone

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• Natural isoflavone
• Phytoestrogen (plant-derived estrogen-like compound)

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Key properties

• Neuroprotective effects
• Can cross the blood-brain barrier

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• Exhibits estrogen-like biological activity (binds to ERα and ERβ)
• Anti-inflammatory properties
• Antioxidant properties
• Regulates MAPK and TGF-β signaling pathways
• Modulates steroid hormone biosynthesis
• Promotes bone metabolism
• High purity used in study (≥ 98%)

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• Protection against neurodegeneration
• Therapeutic for memory impairment and Alzheimer's

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• Dietary supplement in laying hens
• Enhancer of ovarian function
• Improves follicular development
• Reduces follicular atresia
• Increases reproductive hormone levels (LH, FSH, E2, PROG)
• Improves egg production performance (HDEP, HHEP)
• Improves egg quality (eggshell thickness, strength, weight)
• Enhances bone mineral density (BMD) and bone mineral content (BMC)
• Improves bone strength
• Regulates osteogenic gene expression (RUNX2, ALP, OCN, OPG/RANKL)
• Reduces oxidative stress (↓ MDA, ↑ SOD, ↑ CAT)
• Reduces inflammatory cytokines (↓ TNF-α, ↓ IL-1β)

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Classification by use

• Chemicals used as neuroprotective agents
• Chemicals used in blood-brain barrier permeable treatments

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• Chemicals used as phytoestrogenic agents
• Chemicals used in animal nutrition

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A trustworthy factory and manufacturer

Demei Chemical Technology Co., Ltd. is a modern high-tech enterprise integrating R&D, production, and sales. The company's founder, Dr. Arron, born in April 1975, graduated from the School of Mechanical Engineering at Yanshan University and has been engaged in research in the fields of mechanical engineering and chemical synthesis for many years. The company's products focus on the chemical industry, primarily dealing in chemical raw materials and chemical production machinery and equipment. With its strong technical capabilities, advanced production equipment, and strict quality management system, the company has earned the trust of customers worldwide.

1. [Cite:1] HRMS-based profiling of metabolites, metal ions content and in-vitro cholinesterase inhibitory activities of Sonchus wightianus DC plant parts, Electronic Journal of Biotechnology, Volume 79, January 2026, 100702
2. [Cite:2] Dietary genistein supplementation enhances reproductive and bone health in late-laying hens, Poultry Science, Volume 105, Issue 5, May 2026, 106554