2-Methyl-8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzofuro[2,3-b]pyridine
CAS: 1609374-04-0
Category: Organic Pharmaceutical Intermediates
| Purity | ≥97.0% (HPLC); ≥98.0% (HPLC); ≥99.0% (HPLC) |
| Molecular Formula | C18H20BNO3 |
| Molecular Weight | 309.17 |
| Appearance | Off-white to light yellow crystalline powder |
| Packaging | 100 mg, 250 mg, 1 g, 5 g, 10 g, 25 g, or 100 g amber glass bottle or aluminum foil bag with moisture-proof inner liner |
| Testing Indicators | Appearance — Visual inspection; Identification — LC-MS, HRMS, FTIR, 1H NMR, 13C NMR, and 11B NMR; Assay/Purity — HPLC (UV); Related substances — HPLC; Water content — Karl Fischer titration (USP <921>); Residual solvents — GC (USP <467>); Melting point — USP <741>; Elemental impurities — ICP-MS/ICP-OES; Structure confirmation — High-resolution mass spectrometry and multidimensional NMR spectroscopy. |
| Storage Notes | Store tightly sealed in a cool, dry, well-ventilated place. Protect from moisture, air, and direct sunlight. Long-term storage is recommended at 2–8°C under nitrogen or argon. Minimize repeated opening of the container to prevent hydrolysis. |
| Lead Time | 10 days |
An advanced heteroaryl boronic acid pinacol ester (BPin) used as a pharmaceutical and fine chemical intermediate. Primarily employed in Suzuki-Miyaura cross-coupling reactions for the synthesis of kinase inhibitors, heterocyclic drug candidates, OLED materials, agrochemical intermediates, and other π-conjugated functional molecules.