2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl (BINAP)
CAS: 76189-56-5
Category: Organic Intermediates
| Purity | Technical Grade ≥97%; Research Grade ≥98%; Catalyst Grade ≥99%; Chiral Ligand Grade ≥99.5% |
| Molecular Formula | C44H32P2 |
| Molecular Weight | 622.66 |
| Appearance | White to off-white or pale yellow crystalline powder |
| Packaging | 1 g, 5 g, 10 g, 25 g, 100 g fluorinated bottle or amber glass bottle; custom vacuum-sealed packaging available |
| Testing Indicators | Appearance — Visual inspection; Identification — ¹H NMR, ³¹P NMR and HRMS; Purity — HPLC (UV) and/or GC where applicable; Assay — HPLC area normalization; Phosphine oxide impurity — ³¹P NMR or HPLC; Water content — Karl Fischer titration (GB/T 6283); Residual solvents — GC (USP <467>); Melting point — Capillary melting point determination; Elemental analysis — CHN analyzer. |
| Storage Notes | Store in a tightly sealed container under dry nitrogen or argon in a cool, dry, well-ventilated place. Protect from moisture, oxygen, direct sunlight, and strong oxidizing agents. Long-term storage is recommended at 2-8°C. Minimize exposure to air during handling. |
| Lead Time | 10 days |
Widely used as a chiral bidentate phosphine ligand in asymmetric catalysis. Commonly employed in palladium-, rhodium-, ruthenium-, iridium-, and nickel-catalyzed asymmetric hydrogenation, cross-coupling, allylic substitution, C-C bond formation, and fine chemical, pharmaceutical intermediate, and chiral API synthesis. Also used in catalyst development and academic research.