2,2'-Bis(di-p-tolylphosphino)-1,1'-binaphthyl
CAS: 100165-88-6
Category: Organic Intermediates
| Purity | Technical Grade ≥97%; Research Grade ≥98%; Catalyst Grade ≥99%; Chiral Ligand Grade ≥99.5% |
| Molecular Formula | C48H40P2 |
| Molecular Weight | 678.78 |
| Appearance | White to pale yellow crystalline powder |
| Packaging | 1 g, 5 g, 10 g, 25 g, 100 g amber glass bottle or fluorinated bottle; vacuum-sealed aluminum foil bag available for bulk quantities |
| Testing Indicators | Appearance — Visual inspection; Identification — ¹H NMR, ³¹P NMR, ¹³C NMR and HRMS; Purity — HPLC (UV) and/or GC; Assay — HPLC area normalization; Phosphine oxide impurity — ³¹P NMR or HPLC; Water content — Karl Fischer titration (GB/T 6283); Residual solvents — GC (USP <467>); Melting point — Capillary melting point determination; Elemental analysis — CHN elemental analyzer. |
| Storage Notes | Store tightly sealed under dry nitrogen or argon in a cool, dry, well-ventilated area. Protect from moisture, oxygen, heat, and direct sunlight. Avoid prolonged exposure to air during handling. Recommended long-term storage at 2–8°C under an inert atmosphere. |
| Lead Time | 10 days |
A chiral bidentate phosphine ligand widely used in asymmetric catalysis. Commonly employed in palladium-, rhodium-, ruthenium-, iridium-, and nickel-catalyzed asymmetric hydrogenation, Suzuki-Miyaura coupling, Heck reactions, allylic substitution, C-C bond formation, and the synthesis of pharmaceutical intermediates, fine chemicals, and chiral active pharmaceutical ingredients. Frequently used in catalyst screening and ligand development.