(4-(N,N-Dimethylamino)phenyl)di-tert-butylphosphine
CAS: 932710-63-9
Category: Organic Intermediates
| Purity | Technical Grade ≥97%; Research Grade ≥98%; Catalyst Grade ≥99%; High-Purity Grade ≥99.5% |
| Molecular Formula | C18H32NP |
| Molecular Weight | 293.43 |
| Appearance | White to pale yellow crystalline powder or powder |
| Packaging | 1 g, 5 g, 10 g, 25 g, 100 g amber glass bottle or fluorinated HDPE bottle; vacuum-sealed aluminum foil bag under nitrogen for bulk packaging |
| Testing Indicators | Appearance — Visual inspection; Identification — ¹H NMR, ¹³C NMR, ³¹P NMR, FTIR and HRMS; Purity — HPLC (UV) and/or GC; Assay — HPLC area normalization; Phosphine oxide impurity — ³¹P NMR or HPLC; Water content — Karl Fischer titration (GB/T 6283); Residual solvents — GC (USP <467>); Melting point — Capillary melting point determination; Elemental analysis — CHN elemental analyzer. |
| Storage Notes | Store tightly sealed under dry nitrogen or argon in a cool, dry, well-ventilated place. Protect from moisture, oxygen, direct sunlight, and heat. Refrigerated storage at 2–8°C under inert atmosphere is recommended for long-term stability. Avoid repeated exposure to air during handling. |
| Lead Time | 10 days |
A highly electron-rich monodentate phosphine ligand used in transition-metal catalysis. Commonly applied as a ligand for palladium-, nickel-, copper-, and rhodium-catalyzed Buchwald-Hartwig amination, Suzuki-Miyaura coupling, Sonogashira coupling, Heck reaction, Negishi coupling, and other C-C and C-N bond-forming reactions. Widely used in pharmaceutical intermediate synthesis, fine chemicals, catalyst screening, and organometallic research.