2-(Diphenylphosphino)biphenyl
CAS: 13885-09-1
Category: Organic Pharmaceutical Intermediates
| Purity | Research Grade ≥97%; Catalyst Grade ≥98%; High-Purity Grade ≥99% |
| Molecular Formula | C24H19P |
| Molecular Weight | 338.38 |
| Appearance | White to off-white crystalline powder or faint yellow crystalline solid |
| Packaging | 1 g, 5 g, 10 g, 25 g, 100 g amber glass bottle or aluminum foil bag under inert atmosphere |
| Testing Indicators | Appearance — Visual inspection; Identification — ¹H NMR, ¹³C NMR and ³¹P NMR; Molecular weight confirmation — HRMS or LC-MS; Purity — HPLC or GC; Phosphorus content — ³¹P NMR; Water content — Karl Fischer titration (GB/T 6283); Residual solvents — GC (ICH Q3C); Melting point — Capillary melting point apparatus; Elemental analysis — CHN; Heavy metals — ICP-MS. |
| Storage Notes | Store tightly sealed under nitrogen or argon in a cool, dry, well-ventilated place. Protect from air, moisture, direct sunlight, and heat. Long-term storage at 2-8°C under inert atmosphere is recommended. Minimize exposure to oxygen during sampling and handling. |
| Lead Time | 10 days |
An electron-rich monodentate arylphosphine ligand widely used in transition-metal catalysis, especially palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura, Buchwald-Hartwig amination, Negishi, Kumada, Sonogashira, and Stille couplings. It also serves as a precursor for the preparation of advanced phosphine ligands and homogeneous catalysts used in pharmaceutical, agrochemical, and fine chemical synthesis.