(R)-1-[(SP)-2-(Di-tert-butylphosphino)ferrocenyl]ethylbis(2-methylphenyl)phosphine
CAS: 849924-76-1
Category: Organic Intermediates
| Purity | Catalyst Grade ≥97%; High-Purity Grade ≥98%; Chiral Catalyst Grade ≥99% |
| Molecular Formula | C36H46FeP2 |
| Molecular Weight | 596.56 |
| Appearance | Orange to deep red crystalline powder or microcrystalline solid |
| Packaging | 1 g, 5 g, 10 g, 25 g, 100 g amber glass bottle or aluminum foil bag filled under nitrogen |
| Testing Indicators | Appearance — Visual inspection; Identification — 1H NMR, 13C NMR and 31P NMR; Molecular mass — HRMS or LC-MS; Purity — HPLC and/or GC (where applicable); Assay — Quantitative HPLC; Enantiomeric purity — Chiral HPLC; Iron content — ICP-OES (optional); Water content — Karl Fischer titration (GB/T 6283); Residual solvents — GC (ICH Q3C); Melting range — Capillary melting point determination (where applicable). |
| Storage Notes | Store tightly sealed under dry nitrogen or argon in a cool, dry, well-ventilated place. Protect from moisture, air, oxidizing agents and direct sunlight. Long-term storage is recommended at 2–8°C or below. Handle using standard air-free (Schlenk or glovebox) techniques whenever possible. |
| Lead Time | 10 days |
A chiral ferrocene-based bisphosphine ligand widely employed in palladium-, rhodium-, iridium-, nickel- and ruthenium-catalyzed asymmetric coupling, hydrogenation, allylic substitution, C–C bond formation, C–N coupling, and other enantioselective transformations. Frequently used in pharmaceutical process development, fine chemical synthesis, and homogeneous catalysis research.