(R)-1-[(SP)-2-(Diphenylphosphino)ferrocenyl]ethyldi(3,5-xylyl)phosphine

CAS: 184095-69-0

Category: Organic Intermediates

PurityCatalyst Grade ≥97%; High-Purity Grade ≥98%; Chiral Catalyst Grade ≥99%
Molecular FormulaC42H40FeP2
Molecular Weight662.57
AppearanceOrange to dark red crystalline powder
Packaging1 g, 5 g, 10 g, 25 g, or 100 g amber glass bottle sealed under nitrogen or argon
Testing IndicatorsAppearance — Visual inspection; Identification — ¹H NMR, ¹³C NMR and ³¹P NMR; Molecular weight confirmation — HRMS or LC-MS; Purity — HPLC and/or GC; Assay — Quantitative HPLC; Enantiomeric purity — Chiral HPLC; Water content — Karl Fischer titration (GB/T 6283); Residual solvents — GC (ICH Q3C); Iron content — ICP-OES (optional); Elemental analysis — CHN; Melting range — Capillary melting point determination (where applicable).
Storage NotesStore tightly sealed under dry nitrogen or argon in a cool, dry, well-ventilated location. Protect from air, moisture, oxidizing agents and direct sunlight. Recommended storage at 2–8°C or below. Handle under inert atmosphere using Schlenk techniques or in a glovebox whenever possible.
Lead Time10 days
A chiral Josiphos-type ferrocenyl bisphosphine ligand widely used in homogeneous asymmetric catalysis. Commonly coordinated with rhodium, iridium, palladium, ruthenium, nickel and copper catalysts for asymmetric hydrogenation, allylic substitution, cross-coupling, hydroboration, conjugate addition and other enantioselective transformations. Frequently employed in pharmaceutical process development, fine chemical synthesis and catalyst research.