4-Fluoro-N-isopropylaniline
CAS: 70441-63-3
Category: Organic Pharmaceutical Intermediates
| Purity | >=98% (Pharmaceutical Grade) |
| Molecular Formula | C9H12FN |
| Molecular Weight | 153.20 |
| Appearance | Light yellow to brown liquid |
| Packaging | 25 g/glass bottle, 100 g/glass bottle, 500 g/glass bottle, or 1 kg/glass bottle |
| Testing Indicators | Appearance — Visual inspection; Purity — GC-FID; Identification — FTIR (N–H stretch ~3400 cm⁻¹, aromatic C–F ~1200 cm⁻¹) and ¹H NMR (isopropyl doublet ~1.2 ppm); Boiling point — Distillation (ASTM D1078); Density — Hydrometer (ASTM D4052); Refractive index — Abbe refractometer (ASTM D1218); Moisture — Karl Fischer titration (GB/T 6283); Amine content — Acid-base titration (GB/T 9725); Heavy metals — Colorimetric method (GB/T 9741). |
| Storage Notes | Store in a cool, dry, dark place at 2-8°C under an inert atmosphere (nitrogen or argon). Aromatic amines are readily oxidized and discolor upon exposure to air, light, and heat. Keep container tightly sealed. Avoid contact with strong oxidizing agents and strong acids. Handle with nitrile gloves and goggles in a fume hood. |
| Lead Time | 10 days |
An aromatic amine used primarily as an organic synthesis intermediate. It is a key building block in the manufacture of the herbicide flufenacet (used for pre-emergence control of grasses and broadleaf weeds in corn, soybeans, and wheat). It also serves as a pharmaceutical intermediate, where it undergoes acylation, sulfonylation, or isocyanate coupling to prepare amide, sulfonamide, and urea derivatives.