Pyrromethene 546
CAS: 121207-31-6
Category: Fluorescent Dyes
| Purity | ≥98% |
| Molecular Formula | C14H17BF2N2 |
| Molecular Weight | 262.11 |
| Appearance | Red solid |
| Packaging | 250 mg/vial, 500 mg/vial, 1 g/vial |
| Testing Indicators | Appearance — Visual inspection; Identification — ¹H NMR, FTIR, and mass spectrometry (MS); Purity — HPLC (UV detection at ~493 nm) or GC-FID; Melting point — Capillary melting point apparatus; Maximum absorption wavelength (λabs) — UV-Vis spectrophotometer (≈493–498 nm in ethanol/methanol); Maximum emission wavelength (λem) — Fluorescence spectrophotometer (≈505–510 nm); Molar extinction coefficient (ε) — UV-Vis spectrophotometry (≈7–8 × 10⁴ M⁻¹cm⁻¹); Fluorescence quantum yield (Φf) — Relative fluorescence measurement using a standard reference (typically >0.8 in most organic solvents); Moisture — Karl Fischer titration; Residual solvents — GC headspace. |
| Storage Notes | Store at -20 °C. Keep container tightly sealed and protected from light. Store in a dry, well-ventilated area. Avoid prolonged exposure to strong light and moisture. For best stability, store under inert gas (nitrogen or argon). |
| Lead Time | 10 days |
Pyrromethene 546 (PM546) is a high-performance BODIPY fluorescent dye used in drug discovery, bioimaging, assay development, and advanced fluorescence research. It serves as a boron-containing fluorophore for the preparation of fluorescent probes, labeled molecules, analytical methods, and research tools across pharmaceutical, life science, and specialty chemical applications. In drug discovery and chemical biology, it is useful as a BODIPY fluorescent scaffold for probes, conjugates, and assay reagents used in screening, target engagement studies, cellular imaging, and fluorescence-based workflow development. It is also well suited for bioimaging, diagnostics research, sensor development, analytical chemistry, and laser dye applications.