Dabrafenib

CAS: 1195765-45-7

Category: Halogenated aromatics

Purity50 mg Capsules, 75 mg Capsules, USP Reference Standard
Molecular FormulaC23H20F3N5O2S2
Molecular Weight519.56
Appearancewhite to off-white crystalline powder
Packaging1kg/aluminum foil bag or 5kg/plastic container inside a drum.
Testing IndicatorsAppearance — Visual inspection; Identification — IR, LC-MS; Purity — Gradient RP-HPLC; Polymorphic form — XRPD; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Membrane filtration; Sulfonamide dimers — HPLC.
Storage NotesStore in a tightly sealed container under an inert atmosphere in a cool, dry, and dark place, protected from moisture and oxygen.
Lead Time
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days
A B-Raf enzyme inhibitor used as the active pharmaceutical ingredient (API) for the production of targeted therapies for certain types of melanoma and non-small cell lung cancer.