Sonidegib (diphosphate)

CAS: 1218778-77-8

Category: Bis-chlorophenyl-triazine

PurityResearch Grade ≥98%, High-Purity Grade ≥99%, Pharmaceutical Grade ≥99.5%
Molecular FormulaC26H32F3N3O11P2
Molecular Weight681.49
Appearancewhite to off-white crystalline powder
Packaging1 g/amber glass vial, 5 g/lyophilized bottle.
Testing IndicatorsAppearance — Visual inspection; Identification — IR, Phosphate test; Purity — Gradient RP-HPLC; Phosphate — Colorimetry; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Filtration; Benzimidazole impurities — LC-MS.
Storage NotesStored dry and dark at 0-4°C for short term or -20°C for long term in a tightly closed container, protected from light and humidity.
Lead Time
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days
Used as a Smoothened (Smo) antagonist intermediate in the synthesis of hedgehog pathway inhibitors for basal cell carcinoma treatment.