Cobimetinib (racemate)

CAS: 934662-91-6

Category: Benzofuran carboxamide

PurityResearch Grade ≥98%, High-Purity Grade ≥99%, Pharmaceutical Grade ≥99.5%
Molecular FormulaC21H21F3IN3O2
Molecular Weight531.31
Appearancewhite to off-white crystalline powder
Packaging1 g/amber glass vial, 5 g/lyophilized bottle.
Testing IndicatorsAppearance — Visual inspection; Identification — IR, HPLC; Purity — Gradient RP-HPLC; Racemic mixture — Chiral HPLC; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Pour plate; Azetidine impurities — SEC.
Storage NotesStored at -20°C in a tightly closed container under dry, inert conditions, protected from light and humidity.
Lead Time
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days
Used as a MEK inhibitor intermediate in the synthesis of oral targeted therapies for BRAF V600-mutated melanoma in combination regimens.