Cobimetinib (racemate)
CAS: 934662-91-6
Category: Benzofuran carboxamide
| Purity | Research Grade ≥98%, High-Purity Grade ≥99%, Pharmaceutical Grade ≥99.5% |
| Molecular Formula | C21H21F3IN3O2 |
| Molecular Weight | 531.31 |
| Appearance | white to off-white crystalline powder |
| Packaging | 1 g/amber glass vial, 5 g/lyophilized bottle. |
| Testing Indicators | Appearance — Visual inspection; Identification — IR, HPLC; Purity — Gradient RP-HPLC; Racemic mixture — Chiral HPLC; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Pour plate; Azetidine impurities — SEC. |
| Storage Notes | Stored at -20°C in a tightly closed container under dry, inert conditions, protected from light and humidity. |
| Lead Time | 10 days |
Used as a MEK inhibitor intermediate in the synthesis of oral targeted therapies for BRAF V600-mutated melanoma in combination regimens.