Clodronate (disodium tetrahydrate)

CAS: 88416-50-6

Category: Bisphosphonate

PurityReagent Grade ≥98%, High-Purity Grade ≥99%, Pharmaceutical Grade ≥99.5%
Molecular FormulaCH12Cl2Na2O10P2
Molecular Weight362.93
Appearancewhite crystalline powder
Packaging5 kg/aluminum foil bag, 25 kg/plastic drum.
Testing IndicatorsAppearance — Visual inspection; Identification — IR, Sodium test; Purity — Ion-exchange HPLC; Water content — Karl Fischer titration; Sodium — Flame photometry; Heavy metals — ICP-MS; Microbial limits — Pour plate; Phosphonate — Colorimetry; pH — Potentiometry.
Storage NotesStored at 2-8°C in a tightly closed container, protected from light and humidity; maintain hydrate stability by avoiding excessive heat.
Lead Time
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days
Used as a bisphosphonate intermediate in the synthesis of injectable and oral agents for hypercalcemia of malignancy and osteolytic bone lesions.