Bosutinib
CAS: 380843-75-4
Category: Quinoline
| Purity | Research Grade ≥98%, High-Purity Grade ≥99%, Pharmaceutical Grade ≥99.5% |
| Molecular Formula | C26H29Cl2N5O3 |
| Molecular Weight | 530.45 |
| Appearance | white to off-white crystalline powder |
| Packaging | 1 kg/aluminum foil bag, 10 kg/fiber drum. |
| Testing Indicators | Appearance — Visual inspection; Identification — IR, Chiral HPLC; Purity — RP-HPLC; Enantiomeric purity — Chiral HPLC; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Membrane filtration; Aniline dimers — HPLC. |
| Storage Notes | Stored at -20°C in a tightly closed container under dry, inert conditions, away from light and oxidizing agents. |
| Lead Time | 10 days |
Used as a dual Src/Abl tyrosine kinase inhibitor intermediate in the synthesis of oral therapies for chronic myelogenous leukemia with BCR-ABL mutations.