Tolvaptan

CAS: 150683-30-0

Category: Benzazepine

PurityReagent Grade ≥98%, High-Purity Grade ≥99%, Pharmaceutical Grade ≥99.5%
Molecular FormulaC26H25ClN2O3
Molecular Weight448.94
Appearancewhite to off-white crystalline powder
Packaging25 kg/fiber drum, 1 kg/aluminum foil bag.
Testing IndicatorsAppearance — Visual inspection; Identification — IR, HPLC; Purity — Gradient RP-HPLC; Polymorphic form — XRPD; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Pour plate; Benzazepine impurities — LC-MS.
Storage NotesStored in a cool, dry place at room temperature in a tightly closed container, protected from light and moisture.
Lead Time
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days
Used as a selective vasopressin V2-receptor antagonist intermediate in the synthesis of oral agents for hyponatremia and autosomal dominant polycystic kidney disease.