Apalutamide

CAS: 956104-40-8

Category: Diarylthiohydantoin

PurityResearch Grade ≥98%, High-Purity Grade ≥99%, Pharmaceutical Grade ≥99.5%
Molecular FormulaC21H15F4N5O2S
Molecular Weight477.43
Appearancewhite to off-white crystalline powder
Packaging1 kg/aluminum foil bag, 10 kg/plastic drum.
Testing IndicatorsAppearance — Visual inspection; Identification — IR, LC-MS; Purity — RP-HPLC; Polymorphic form — XRPD; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Filtration; Thiohydantoin impurities — SEC.
Storage NotesStored at -20°C in a tightly closed container under inert atmosphere, away from light, moisture, and oxidizing agents.
Lead Time10 days
Used as a nonsteroidal androgen receptor antagonist intermediate in the synthesis of oral therapies for non-metastatic castration-resistant prostate cancer.