Ivosidenib
CAS: 1448347-49-6
Category: Pharmaceutical Intermediates
| Purity | Research Grade ≥98%, High-Purity Grade ≥99%, Pharmaceutical Grade ≥99.5% |
| Molecular Formula | C28H22ClF3N6O3 |
| Molecular Weight | 582.96 |
| Appearance | white to off-white crystalline powder |
| Packaging | 1 g/amber glass vial, 5 g/lyophilized bottle. |
| Testing Indicators | Appearance — Visual inspection; Identification — IR, Chiral HPLC; Purity — Gradient RP-HPLC; Enantiomeric purity — Chiral HPLC; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Membrane filtration; IDH1 mutants — SEC. |
| Storage Notes | Stored at -20°C in a tightly closed container under dry, inert conditions, protected from light and humidity. |
| Lead Time | Deprecated: htmlspecialchars(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.demeichem.com/config/helpers.php on line 28 days |
Used as an IDH1 inhibitor intermediate in the synthesis of oral targeted therapies for acute myeloid leukemia with IDH1 mutations.