Sitagliptin (phosphate monohydrate)

CAS: 654671-77-9

Category: DPP-4 Inhibitors

PurityReagent Grade ≥98%, High-Purity Grade ≥99%, Technical Grade ≥95%
Molecular FormulaC16H20F6N5O6P
Molecular Weight523.32
AppearanceWhite to off-white crystalline powder
Packaging25 kg/fiber drum, 5 kg/aluminum foil bag.
Testing IndicatorsAppearance — Visual inspection; Identification — IR, Phosphate test; Purity — Gradient RP-HPLC; Water content — Karl Fischer titration; Phosphate — Colorimetry; Residual solvents — HS-GC; Heavy metals — ICP-MS; Microbial limits — Filtration; Enantiomeric purity — Chiral HPLC.
Storage NotesStored in a cool, dry place at 15-30°C in a tightly closed container, protected from light and moisture to maintain monohydrate stability.
Lead Time
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days
Used as a DPP-4 inhibitor intermediate in the synthesis of oral antidiabetic agents for type 2 diabetes to prolong incretin activity.