Sitagliptin (phosphate monohydrate)
CAS: 654671-77-9
Category: DPP-4 Inhibitors
| Purity | Reagent Grade ≥98%, High-Purity Grade ≥99%, Technical Grade ≥95% |
| Molecular Formula | C16H20F6N5O6P |
| Molecular Weight | 523.32 |
| Appearance | White to off-white crystalline powder |
| Packaging | 25 kg/fiber drum, 5 kg/aluminum foil bag. |
| Testing Indicators | Appearance — Visual inspection; Identification — IR, Phosphate test; Purity — Gradient RP-HPLC; Water content — Karl Fischer titration; Phosphate — Colorimetry; Residual solvents — HS-GC; Heavy metals — ICP-MS; Microbial limits — Filtration; Enantiomeric purity — Chiral HPLC. |
| Storage Notes | Stored in a cool, dry place at 15-30°C in a tightly closed container, protected from light and moisture to maintain monohydrate stability. |
| Lead Time | 10 days |
Used as a DPP-4 inhibitor intermediate in the synthesis of oral antidiabetic agents for type 2 diabetes to prolong incretin activity.