Tetrahydrobiopterin

CAS: 17528-72-2

Category: Pteridine

PurityPharmaceutical Grade (≥98%), High-Purity Biochemical Grade (≥95%), Research Grade.
Molecular FormulaC9H15N5O3
Molecular Weight241.25
AppearanceWhite to off-white crystalline powder, very hygroscopic and light-sensitive
Packaging1 g/amber glass vial, 5 g/lyophilized bottle.
Testing IndicatorsAppearance — Visual inspection; Specific rotation — Polarimetry; Identification — IR, UV (280 nm); Purity — RP-HPLC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Membrane filtration; Pteridine impurities — LC-MS; pH — Potentiometry.
Storage NotesStored as lyophilized powder at -80°C or -20°C in a tightly closed container under inert atmosphere, protected from light, air, and moisture.
Lead Time
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days
Used as a cofactor intermediate in the synthesis of treatments for phenylketonuria (PKU) and neurotransmitter deficiencies via oral sapropterin formulations.