Rucaparib (phosphate)

CAS: 459868-92-9

Category: Phthalazinone

PurityReagent Grade ≥98%, High-Purity Grade ≥99%, Technical Grade ≥95%
Molecular FormulaC19H21FN3O5P
Molecular Weight421.36
AppearanceWhite to off-white crystalline powder
Packaging1 kg/aluminum foil bag, 10 kg/fiber drum.
Testing IndicatorsAppearance — Visual inspection; Identification — IR, Phosphate test; Purity — RP-HPLC; Phosphate — Colorimetry; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Membrane filtration; PARP inhibitor impurities — LC-MS.
Storage NotesStored at -20°C in a tightly closed container under dry, inert conditions, away from light and oxidizing agents.
Lead Time10 days
Used as a PARP inhibitor intermediate in the synthesis of oral targeted therapies for BRCA-mutated ovarian cancer and prostate cancer.