Trimethylsilyl trifluoromethanesulfonate
CAS: 27607-77-8
Category: Organosilicon Compounds
| Purity | Reagent Grade ≥99%, Ultra-Dry Grade ≥99.5% |
| Molecular Formula | C4H9F3O3SSi |
| Molecular Weight | 222.26 |
| Appearance | Colorless to pale yellow liquid, but often darkens to brown over time |
| Packaging | 25 g/glass bottle, 100 g/glass bottle, or 200 kg/steel drum with polyethylene liner |
| Testing Indicators | Appearance — Visual inspection; Purity — GC; Moisture — Karl Fischer titration; Identification — FTIR (SO₃ ~1360 cm⁻¹, Si–O–S band); Reactivity — Silylation test with alcohol standard. |
| Storage Notes | Store in a cool, dark, dry, and well-ventilated place (often recommended <15℃). It is highly corrosive (causes severe burns) and reacts violently with water (moisture-sensitive). Keep the container tightly closed under an inert gas atmosphere, away from heat, sparks, and flame. |
| Lead Time | Deprecated: htmlspecialchars(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.demeichem.com/config/helpers.php on line 28 days |
One of the most powerful and versatile silylating agents, acting as a Lewis Acid catalyst and a strong TMS source. It is widely used in organic synthesis for highly efficient silylation reactions, protection of OH groups, and as a catalyst for reactions like the formation of silyl enol ethers and glycosylation.