Macitentan
CAS: 441798-33-0
Category: Benzothiadiazine
| Purity | Reagent Grade ≥98%, High-Purity Grade ≥99%, Technical Grade ≥95% |
| Molecular Formula | C19H20Br2N6O4S |
| Molecular Weight | 588.27 |
| Appearance | White to off-white crystalline powder |
| Packaging | 1g/5g/10g or 25kg/cardboard drum or 1kg/aluminum foil bag |
| Testing Indicators | Appearance — Visual inspection; Identification — IR, HPLC; Purity — Gradient RP-HPLC; Polymorphic form — XRPD; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Pour plate; Sulfonamide dimers — SEC. |
| Storage Notes | Stored in a cool, dry, and well-ventilated place in a tightly closed container with desiccants, protected from light, moisture, and heat, away from incompatible materials and direct sunlight. |
| Lead Time | Deprecated: htmlspecialchars(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.demeichem.com/config/helpers.php on line 28 days |
Used as a dual endothelin receptor antagonist (ERA) in the synthesis of oral treatments for pulmonary arterial hypertension (PAH) to improve exercise capacity and delay progression.