Entacapone

CAS: 130929-57-6

Category: Nitro Compounds

PurityReagent Grade ≥98%, High-Purity Grade ≥99%, Technical Grade ≥95%
Molecular FormulaC14H15N3O5
Molecular Weight305.29
AppearanceYellow to orange crystalline powder
Packaging1g/5g/10g or 25kg/cardboard drum or 1kg/aluminum foil bag
Testing IndicatorsAppearance — Visual inspection; Identification — IR, UV; Purity — Gradient RP-HPLC; Geometric isomers — HPLC; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Membrane filtration; Nitrocatechol impurities — LC-MS.
Storage NotesStored in a cool, dry, and well-ventilated place in a tightly closed, light-resistant container, away from incompatible materials, heat, direct sunlight, and sources of ignition.
Lead Time
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days
Used as a catechol-O-methyltransferase (COMT) inhibitor in combination with levodopa/carbidopa for adjunctive therapy in Parkinson's disease to prolong levodopa effects.