108-24-7 | Acetic Anhydride

Chemical type

• Acylating agent
• Carboxylic acid anhydride

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• Hydrogen bond acceptor in deep eutectic solvent (DES)

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Key properties

• Strong electrophile for nucleophilic substitution in acylation reactions
• Used in excess to enhance reaction rate and conversion
• Reacts with furan in a 1:3 molar ratio under optimized conditions for high yield
• Enables solvent-free, green processes when paired with heterogeneous catalysts

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• Activated by hydrogen bonding with ChCl
• Electrophilic carbonyl for nucleophilic attack by OH groups
• Produces acetic acid as byproduct
• Enables acetylation of α-/γ-OH and phenolic OH in lignin

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• Acylating reagent in Friedel-Crafts acylation of furan to form 2-acylfuran
• Alternative to carboxylic acids in acylation reactions over solid acid catalysts
• Employed in liquid-phase reactions at mild temperatures (e.g., 50°C)

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• Functional fractionation of lignin from lignocellulose
• Protection of native lignin structure via acetylation
• Suppression of lignin re-condensation
• Tuning DES composition with acetic acid for improved lignin dissolution

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Classification by use

• Chemicals used as reagents in organic acylation
• Chemicals used in green catalytic processes (solventless)
• Chemicals used in synthesis of pharmaceutical and aroma intermediates

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• Chemicals used in biomass pretreatment
• Chemicals used as acetylation agents

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A trustworthy factory and manufacturer

Demei Chemical Technology Co., Ltd. is a modern high-tech enterprise integrating R&D, production, and sales. The company's founder, Dr. Arron, born in April 1975, graduated from the School of Mechanical Engineering at Yanshan University and has been engaged in research in the fields of mechanical engineering and chemical synthesis for many years. The company's products focus on the chemical industry, primarily dealing in chemical raw materials and chemical production machinery and equipment. With its strong technical capabilities, advanced production equipment, and strict quality management system, the company has earned the trust of customers worldwide.

1. [Cite:1] Sustainable friedel-crafts acylation of Acetic Anhydride using nanocrystalline ZSM-5: A green catalytic approach, Chemical Engineering Journal Advances, Volume 25, March 2026, 100970
2. [Cite:2] A biomass refining strategy combining liquid hot water and deep eutectic solvent (DES) treatment: Acetylation fractionation of uncondensed lignin by acetic anhydride DES, Industrial Crops and Products, Volume 234, 15 October 2025, 121614