137-58-6 | Lidocaine

Chemical type

• Amide-type local anesthetic

^[1]

• Amide local anesthetic

^[2]

Key properties

• Provides local anesthesia by blocking nerve signals
• Concentration: 10 mg/ml
• Administered volume: Up to 10 ml

^[1]

• Inhibits sodium ion channels on nerve cells and cardiomyocytes
• Provides analgesic, anti-hyperalgesia, and anti-inflammatory effects
• Stabilizes nerve cell membranes by inhibiting transmembrane sodium and potassium exchange
• Reduces cerebral oxygen metabolism
• Neuroprotective against neuroinflammation

^[2]

• Infiltrated into subcutaneous tissues, abdominal wall layers, and organ capsules during biopsy procedures
• Reduces pain during skin puncture and needle advancement

^[1]

• Local anesthetic for surgery
• Antiarrhythmic drug for acute ventricular tachycardia and premature ventricular beats
• Perioperative intravenous infusion to reduce postoperative nausea, vomiting, and cognitive decline
• Mitigates neuroinflammation and improves cerebral oxygen homeostasis in one-lung ventilation procedures
• Administered as bolus (1.5 mg/kg) followed by continuous infusion (1.5 mg/kg/hr) during anesthesia

^[2]

Classification by use

• Chemicals used in medical anesthesia
• Chemicals used in invasive procedures like biopsies

^[1]

• Anesthetics (local and general)
• Antiarrhythmics
• Analgesics and anti-inflammatory agents
• Neuroprotective agents in surgery

^[2]

A trustworthy factory and manufacturer

Demei Chemical Technology Co., Ltd. is a modern high-tech enterprise integrating R&D, production, and sales. The company's founder, Dr. Arron, born in April 1975, graduated from the School of Mechanical Engineering at Yanshan University and has been engaged in research in the fields of mechanical engineering and chemical synthesis for many years. The company's products focus on the chemical industry, primarily dealing in chemical raw materials and chemical production machinery and equipment. With its strong technical capabilities, advanced production equipment, and strict quality management system, the company has earned the trust of customers worldwide.

1. [Cite:1] A core needle biopsy combined with novel spectroscopic probe for in vivo tissue classification – A pilot study on piglets, Biomedical Engineering Advances, Volume 10, November 2025, 100191
2. [Cite:2] Lidocaine mitigates cognitive decline in elderly patients after video-assisted thoracoscopic surgery: A double-blind randomized controlled clinical trial, Brain Disorders, Volume 21, March 2026, 100308