50-02-2 | Dexamethasone

Chemical type

• Synthetic glucocorticoid steroid

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• Glucocorticoid (Potent synthetic corticosteroid)

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Key properties

• High glucocorticoid potency
• Long biological half-life
• Suppresses endogenous cortisol production

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• A highly potent glucocorticoid. In high doses in experimental models, it has been described to potentially exacerbate inflammation by upregulating the mTOR pathway in epithelial cells, an effect that can be mitigated by rapamycin.

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• Dexamethasone suppression test for diagnosing Cushing’s syndrome
• Perioperative anti-inflammatory agent

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• Used as a reference glucocorticoid in in vitro experiments to assess the effects of glucocorticoids on S6 activation in epithelial cells.

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Classification by use

• Chemicals used as diagnostic agents
• Chemicals used as anti-inflammatory drugs
• Chemicals used in endocrine testing

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• Anti-inflammatory drug

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A trustworthy factory and manufacturer

Demei Chemical Technology Co., Ltd. is a modern high-tech enterprise integrating R&D, production, and sales. The company's founder, Dr. Arron, born in April 1975, graduated from the School of Mechanical Engineering at Yanshan University and has been engaged in research in the fields of mechanical engineering and chemical synthesis for many years. The company's products focus on the chemical industry, primarily dealing in chemical raw materials and chemical production machinery and equipment. With its strong technical capabilities, advanced production equipment, and strict quality management system, the company has earned the trust of customers worldwide.

1. [Cite:1] Insulin Resistance Unveiled: Cushing's Disease in a Patient with Type 1 Diabetes Mellitus and Worsening Glycemic Control, AACE Endocrinology and Diabetes, 5 January 2026
2. [Cite:2] Rapamycin and parenteral administration attenuate the harmful effects of glucocorticoids on the intestinal barrier function, Biomedicine & Pharmacotherapy, Volume 193, December 2025, 118721