9002-60-2 | Adrenocorticotropic Hormone (ACTH)

Chemical type

• Peptide hormone

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• Polypeptide hormone

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Key properties

• Stimulates adrenal cortisol synthesis
• Secreted by the anterior pituitary gland

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• Stimulates adrenal cortex to produce glucocorticoids like cortisol
• Markedly elevated in ectopic Cushing syndrome (e.g., levels up to 450 pg/mL)
• Not suppressed by high-dose dexamethasone in ectopic cases

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• Diagnostic marker to distinguish ACTH-dependent vs ACTH-independent Cushing’s syndrome

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• Diagnostic biomarker for distinguishing pituitary vs. ectopic Cushing syndrome
• Pathological staining to confirm tumor secretion
• Therapeutic target in managing hypercortisolism

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Classification by use

• Chemicals used as endocrine biomarkers
• Chemicals involved in hormonal signaling

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• Hormones in endocrine diagnostics
• Biomarkers for neuroendocrine tumors

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A trustworthy factory and manufacturer

Demei Chemical Technology Co., Ltd. is a modern high-tech enterprise integrating R&D, production, and sales. The company's founder, Dr. Arron, born in April 1975, graduated from the School of Mechanical Engineering at Yanshan University and has been engaged in research in the fields of mechanical engineering and chemical synthesis for many years. The company's products focus on the chemical industry, primarily dealing in chemical raw materials and chemical production machinery and equipment. With its strong technical capabilities, advanced production equipment, and strict quality management system, the company has earned the trust of customers worldwide.

1. [Cite:1] Insulin Resistance Unveiled: Cushing's Disease in a Patient with Type 1 Diabetes Mellitus and Worsening Glycemic Control, AACE Endocrinology and Diabetes, 5 January 2026
2. [Cite:2] Ectopic Cushing Syndrome due to an Adrenocorticotropic Hormone-Producing Pheochromocytoma, AACE Endocrinology and Diabetes, 2 January 2026