501-36-0 | Resveratrol

Chemical type

• Stilbene (stilbenoids)

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• Polyphenolic stilbene phytoalexin

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Key properties

• Synthesized from phenylalanine via p-coumaroyl-CoA
• Broad antifungal activity (e.g., against B. cinerea)
• Role in oomycete resistance
• Regulated by MYB/WRKY TFs (e.g., VvMYB14, VvWRKY8) and stress signals (pathogen, UV)

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• Cardioprotective against norepinephrine-induced damage; antioxidant that reduces oxidative stress (e.g., lowers MDA levels); improves cardiomyocyte viability, morphology, and contractile function (e.g., preserves peak shortening, maximal velocities of shortening/re-lengthening); acts partly via SOD/FOXO1 pathway; decreases FOXO1 and acetyl-FOXO1 protein expression while increasing SIRT1 expression and FOXO1 transcriptional activity; anti-proliferative on cardiac fibroblasts without increasing cell death; non-toxic at low doses (e.g., 30 μM/L).

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• Plant defense in grapevine against fungi and oomycetes
• Antioxidant and signaling molecule in immune responses

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• Protects adult rat cardiomyocytes from norepinephrine-induced contractile dysfunction, oxidative stress, and reduced viability; prevents morphological changes (e.g., maintains rod-shaped cells); inhibits cardiac fibroblast proliferation, potentially reducing cardiac fibrosis; potential therapeutic for heart failure by countering sympathetic overactivation and oxidative damage.

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Classification by use

• Phytoalexins used in antifungal and anti-oomycete defense
• Phenolic compounds for pathogen resistance

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• Cardioprotective agents
• Antioxidants

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A trustworthy factory and manufacturer

Demei Chemical Technology Co., Ltd. is a modern high-tech enterprise integrating R&D, production, and sales. The company's founder, Dr. Arron, born in April 1975, graduated from the School of Mechanical Engineering at Yanshan University and has been engaged in research in the fields of mechanical engineering and chemical synthesis for many years. The company's products focus on the chemical industry, primarily dealing in chemical raw materials and chemical production machinery and equipment. With its strong technical capabilities, advanced production equipment, and strict quality management system, the company has earned the trust of customers worldwide.

1. [Cite:1] Redefining phytoalexins as engineered defenses for plant disease resistance, Current Plant Biology, Volume 45, January 2026, 100577
2. [Cite:1] Resveratrol improves contractile dysfunction, cell viability and oxidative stress in adult rat cardiomyocytes exposed to norepinephrine via SOD/FOXO1, Journal of Functional Foods, Volume 138, March 2026, 107174