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Methylsulfinylmethane

CAS No.: 67-68-5

  • Molecular Formula: C₂H₆OS
  • Molecular Weight: 78.14 g/mol

Chemical type

  • Polar aprotic solvent
  • Organosulfur compound
[1]
  • Organic solvent
[2]
  • Polar aprotic solvent
[3]

Key properties

  • Common laboratory solvent
  • Cryoprotectant
  • Penetration enhancer
[1]
  • Used at 1% concentration as vehicle
  • Dissolves PD98059 for intraperitoneal injection
  • No therapeutic effect alone (serves as control vehicle)
  • Commonly used in pharmacological studies for drug delivery
[2]
  • Penetrates biological membranes readily
  • Hygroscopic
  • Miscible with water and most organic solvents
[3]
  • Used as a vehicle/control solvent in cell culture drug validation experiments in the study (e.g., for bexarotene treatment)
[1]
  • Vehicle for administering PD98059 in EAE treatment
  • Control substance in experimental groups
  • Solvent in biochemical and molecular assays
[2]
  • Cryoprotectant for cell freezing (inferred)
  • Solvent for water-insoluble substances in biological assays (inferred)
[3]

Classification by use

  • Laboratory solvents
  • Chemical reagents
[1]
  • Chemicals used as solvents
  • Chemicals used in drug delivery vehicles
  • Chemicals used in pharmacological experiments
[2]
  • Chemicals used in cell preservation
[3]

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  1. [Cite:1] Anoikis- and m6A-related lncRNA analysis to identify prognostic indicators in liver hepatocellular carcinoma, Electronic Journal of Biotechnology, Volume 79, January 2026, 100701
  2. [Cite:2] Mitogen-activated protein kinase inhibitor PD98059 improves neuroimmune dysfunction in experimental autoimmune encephalomyelitis in SJL/J mice through the inhibition of nuclear factor-kappa B signaling in B cells, Brain Research Bulletin, Volume 194, March 2023, Pages 45-53
  3. [Cite:3] Penicillin–Streptomycin Treatment Rewires Core Metabolic and Ribosomal Programs in HepG2 Cells, J. Proteome Res. 2026, 25, 2, 1082–1094