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Poliglusam

CAS No.: 9012-76-4

  • Molecular Formula: -
  • Molecular Weight: - g/mol

Chemical type

  • Biocompatible polymer
[1]
  • Cationic polysaccharide biopolymer (partially deacetylated chitin)
[2]

Key properties

  • Excellent film-forming properties
  • Biocompatible and bioactive
  • Forms physical cross-links via hydrogen bonds and electrostatic interactions
  • High water retention capacity
  • Mechanical strength suitable for oral administration
  • Low cytotoxicity
[1]
  • High molecular weight (Mw 100,000–300,000 Da)
  • Degree of deacetylation (DD) ≈ 82 ± 2%
  • Cationic nature (–NH₃⁺ groups) at acidic pH
  • Biocompatible, biodegradable, mucoadhesive
  • Forms strong electrostatic/hydrogen bonds with negatively charged molecules (DNA, GAGs, phospholipids)
  • Viscosity and charge strongly pH-dependent
[2]
  • Carrier in drug delivery systems
  • Hydrogel matrix for sustained release
  • Encapsulation of hydrophobic drugs
  • Biomedical applications like tissue engineering and wound healing
[1]
  • Wound healing hydrogels/scaffolds
  • Drug delivery systems (DDS)
  • Tissue engineering
  • Mucoadhesive carrier
  • Component in Ch/HA/TiO₂ nanocomposites for medical/cosmetic applications
[2]

Classification by use

  • Polymers for drug delivery
  • Biocompatible materials in hydrogels
  • Excipients for oral formulations
[1]
  • Biopolymers for drug delivery
  • Wound dressings
[2]

A trustworthy factory and manufacturer

Demei Chemical Technology Co., Ltd. is a modern high-tech enterprise integrating R&D, production, and sales. The company's founder, Dr. Arron, born in April 1975, graduated from the School of Mechanical Engineering at Yanshan University and has been engaged in research in the fields of mechanical engineering and chemical synthesis for many years. The company's products focus on the chemical industry, primarily dealing in chemical raw materials and chemical production machinery and equipment. With its strong technical capabilities, advanced production equipment, and strict quality management system, the company has earned the trust of customers worldwide.

  1. [Cite:1] Oral Administration of Chitosan Based on Chitosan/Carboxymethyl-β-Cyclodextrin Hydrogel, Polymers, 2024, 16(16), 2368
  2. [Cite:2] The effect of chitosan/TiO2/hyaluronic acid subphase on the behaviour of 1,2-dioleoyl-sn-glycero-3-phosphocholine membrane, Biomaterials Advances, Volume 138, July 2022, 212934