Polyquaternium 1
CAS: 75345-27-6
Category: Polymers
| Purity | Cosmetic Grade ≥95.0%, Pharmaceutical Grade ≥98.0% |
| Molecular Formula | C21H38ClN3O |
| Molecular Weight | Approx. 387.99 (monomer unit) |
| Appearance | White to pale yellow powder, flakes, or hygroscopic solid with slight characteristic odor |
| Packaging | 25 kg fiber drum with inner polyethylene liner, 25 kg paper bag, or customized moisture-proof packaging |
| Testing Indicators | Appearance — Visual inspection; Identification — FTIR spectroscopy and NMR analysis; Polymer content — HPLC or titration method; Quaternary ammonium content — Potentiometric titration; Molecular weight distribution — GPC/SEC analysis; Water content — Karl Fischer titration (ASTM E203); pH value — Potentiometric measurement; Residual solvents — GC analysis; Heavy metals — ICP-OES analysis; Microbial limit test — USP <61>/<62> or relevant pharmacopeial methods; Antimicrobial effectiveness test — USP <51> preservative efficacy testing. |
| Storage Notes | Store in a cool, dry, and well-ventilated area. Keep containers tightly sealed and protected from moisture, heat, and direct sunlight. Avoid contact with strong oxidizing agents and incompatible ionic compounds. Due to its hygroscopic nature, minimize exposure to humid environments and keep packaging closed after use. |
| Lead Time | 10 days |
Polyquaternium 1 is a cationic polymer widely used as an antimicrobial preservative and conditioning agent in pharmaceutical and personal care formulations. It is mainly applied in ophthalmic solutions, contact lens care products, cosmetics, and personal hygiene products. Due to its quaternary ammonium structure, it provides broad-spectrum antimicrobial activity against bacteria and fungi while also improving surface conditioning, substantivity, and product stability.