(S)-1-[(R)-2-(Di-tert-butylphosphino)ferrocenyl]ethylbis(2-methylphenyl)phosphine
CAS: 849924-77-2
Category: Organic Intermediates
| Purity | Chemical Purity ≥98%; HPLC ≥99%; Enantiomeric Excess (ee) ≥99% |
| Molecular Formula | C38H46FeP2 |
| Molecular Weight | 620.56 |
| Appearance | Yellow to deep orange crystalline powder |
| Packaging | 1 g, 5 g, 10 g, 25 g, 100 g amber glass bottle with PTFE-lined cap or sealed aluminum foil bag under nitrogen; customized bulk packaging available |
| Testing Indicators | Appearance — Visual inspection; Identification — 1H NMR, 13C NMR, 31P NMR, FTIR and HRMS; Purity — HPLC and/or GC; Enantiomeric purity — Chiral HPLC; Phosphorus integrity — 31P NMR; Iron content — ICP-OES or ICP-MS; Moisture — Karl Fischer titration (GB/T 6283); Melting point — Capillary melting point determination; Elemental analysis — CHN elemental analyzer; Residue on ignition — Gravimetric analysis. |
| Storage Notes | Store tightly sealed under dry nitrogen or argon in a cool, dry, well-ventilated place. Protect from moisture, oxygen, direct sunlight and heat. Recommended storage temperature is 2–8°C for long-term stability. Handle under an inert atmosphere whenever possible and reseal immediately after use. |
| Lead Time | 10 days |
A chiral Josiphos-type ferrocene bisphosphine ligand widely used in homogeneous transition-metal catalysis. Frequently employed with rhodium, iridium, palladium, ruthenium and copper catalysts for asymmetric hydrogenation, asymmetric allylic substitution, hydroboration, Buchwald-Hartwig amination, Suzuki-Miyaura coupling and other enantioselective transformations. Extensively used in pharmaceutical intermediate synthesis, fine chemical manufacturing and catalyst development.