(2S)-1-((4S)-4,5-Dihydro-4-(1-methylethyl)-2-oxazolyl)-2-(diphenylphosphino)ferrocene
CAS: 163169-29-7
Category: Organic Intermediates
| Purity | Catalyst Grade ≥97%; High-Purity Grade ≥98%; Chiral Catalyst Grade ≥99% |
| Molecular Formula | C30H30FeNOP |
| Molecular Weight | 507.38 |
| Appearance | Orange to reddish-orange crystalline powder |
| Packaging | 1 g, 5 g, 10 g, 25 g, or 100 g amber glass bottle sealed under nitrogen or argon |
| Testing Indicators | Appearance — Visual inspection; Identification — ¹H NMR, ¹³C NMR and ³¹P NMR; Molecular weight confirmation — HRMS or LC-MS; Purity — HPLC and/or GC; Assay — Quantitative HPLC; Optical purity — Chiral HPLC; Water content — Karl Fischer titration (GB/T 6283); Residual solvents — GC (ICH Q3C); Iron content — ICP-OES (optional); Melting range — Capillary melting point determination (where applicable). |
| Storage Notes | Store tightly sealed under dry nitrogen or argon in a cool, dry, well-ventilated location. Protect from air, moisture, strong oxidizing agents, and direct sunlight. Recommended long-term storage at 2–8°C or below. Handle using glovebox or Schlenk techniques whenever possible. |
| Lead Time | 10 days |
A chiral ferrocenyl phosphine-oxazoline (PHOX) ligand widely used in asymmetric catalysis. Commonly employed as a ligand for palladium, iridium, rhodium, ruthenium, and copper catalysts in asymmetric allylic substitution, hydrogenation, conjugate addition, cyclization, and other enantioselective transformations. Frequently utilized in pharmaceutical research, fine chemical synthesis, and catalyst development.