L-cis-Diltiazem hydrochloride
CAS: 42399-54-2
Category: Pharmaceutical Intermediates
| Purity | ≥98% (typical research grade), >97% |
| Molecular Formula | C₂₂H₂₇ClN₂O₄S |
| Molecular Weight | 450.98 |
| Appearance | White to off-white powder/solid |
| Packaging | 10 mg, 50 mg, 100 mg, or 250 mg in amber glass vials; bulk quantities (1 g, 5 g, 10 g) available upon request for custom synthesis. |
| Testing Indicators | Appearance — Visual inspection; Purity — HPLC (area percentage) with UV detection; Identification — LC-MS/MS and/or FTIR; Chiral Purity — Chiral HPLC; Water Content — Karl Fischer titration; Residual Solvents — GC (if applicable). |
| Storage Notes | Store at room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, keep tightly sealed in a cool, dry place, protected from light. Solutions are often prepared fresh or stored in aliquots at -20°C to prevent degradation. |
| Lead Time | 10 days |
Primarily used as a research tool as a selective inhibitor of cyclic nucleotide-gated (CNG) channels (CNGA1, CNGA2, CNGA3). Also employed as a chiral reference standard and impurity marker for analytical method development and quality control in diltiazem-related pharmaceutical research. Available for custom synthesis for non-clinical research use only.