Platinum(IV) diammine dichloro succinate
CAS: 1189745-30-9
Category: Inorganic Chemicals
| Purity | ≥95% |
| Molecular Formula | C4H12Cl2N2O5Pt |
| Molecular Weight | 434.14 |
| Appearance | Yellow powder |
| Packaging | 100 mg/glass vial, 500 mg/glass vial, or 1 g/glass vial |
| Testing Indicators | Appearance — Visual inspection; Purity — HPLC area percentage (≥95%); Identification — FTIR, ¹H NMR, and ESI-MS; Platinum content — ICP-OES or ICP-MS; Moisture — Karl Fischer titration; Succinate ligand content — HPLC or ion chromatography. |
| Storage Notes | Store in a cool, dry, well-ventilated area. Keep container tightly sealed and refrigerated. Store under inert gas (nitrogen or argon) to prevent moisture absorption. Protect from light. Keep away from strong oxidizing agents and reducing agents. |
| Lead Time | 10 days |
Platinum(IV) complex investigated primarily as an anticancer prodrug. More kinetically inert than Pt(II) species (e.g., cisplatin), improving blood stability. Reduced inside cells to active Pt(II) species that bind DNA. The free carboxylic acid on the succinate ligand enables further derivatization for improved solubility, lipophilicity, or targeted delivery. Used in preclinical research for exploring reduction activation, DNA binding, and cytotoxicity.