tert-Butyldimethylsilyl chloride
CAS: 18162-48-6
Category: Organosilicon Compounds
| Purity | Reagent Grade ≥97%, High-Purity Grade ≥99% |
| Molecular Formula | C6H15ClSi |
| Molecular Weight | 150.72 |
| Appearance | White to off-white crystalline low-melting solid or flakes |
| Packaging | 25 g/glass bottle, 100 g/glass bottle, or 200 kg/steel drum with polyethylene liner |
| Testing Indicators | Appearance — Visual inspection; Melting point — Capillary method (GB/T 617); Purity — GC or HPLC; Chlorine content — Volhard titration; Moisture — Karl Fischer titration; Identification — FTIR (Si–Cl ~580 cm⁻¹), NMR; Protecting reactivity — Standard silylation test with alcohol. |
| Storage Notes | Store locked up in a cool, dry, and well-ventilated place. It is generally a moisture-sensitive corrosive solid and should be kept in a tightly closed, corrosive-resistant container. |
| Lead Time | Deprecated: htmlspecialchars(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.demeichem.com/config/helpers.php on line 28 days |
A very common and versatile silylating reagent used in organic synthesis for the protection of hydroxyl (OH) groups (e.g., alcohols) to form tert-butyldimethylsilyl (TBDMS) ethers. TBDMS is a popular, stable, and easily cleaved protecting group.