Nintedanib

CAS: 656247-17-5

Category: Indole Compounds

PurityResearch Grade ≥98%, High-Purity Grade ≥99%, Pharmaceutical Grade ≥99.5%
Molecular FormulaC31H33N5O4
Molecular Weight539.62
Appearanceyellow to orange crystalline powder
Packaging1 g/amber glass vial, 5 g/plastic drum.
Testing IndicatorsAppearance — Visual inspection; Identification — IR, LC-MS; Purity — Gradient RP-HPLC; Polymorphic form — XRPD; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Filtration; Indolinone impurities — SEC.
Storage NotesStored at -20°C in a tightly closed container under inert atmosphere, away from light, heat, and oxidizing agents.
Lead Time
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days
Used as a tyrosine kinase inhibitor intermediate in the synthesis of oral agents for idiopathic pulmonary fibrosis and non-small cell lung cancer.