Nintedanib
CAS: 656247-17-5
Category: Indole Compounds
| Purity | Research Grade ≥98%, High-Purity Grade ≥99%, Pharmaceutical Grade ≥99.5% |
| Molecular Formula | C31H33N5O4 |
| Molecular Weight | 539.62 |
| Appearance | yellow to orange crystalline powder |
| Packaging | 1 g/amber glass vial, 5 g/plastic drum. |
| Testing Indicators | Appearance — Visual inspection; Identification — IR, LC-MS; Purity — Gradient RP-HPLC; Polymorphic form — XRPD; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Filtration; Indolinone impurities — SEC. |
| Storage Notes | Stored at -20°C in a tightly closed container under inert atmosphere, away from light, heat, and oxidizing agents. |
| Lead Time | 10 days |
Used as a tyrosine kinase inhibitor intermediate in the synthesis of oral agents for idiopathic pulmonary fibrosis and non-small cell lung cancer.