Gefitinib

CAS: 184475-35-2

Category: Quinoline

PurityResearch Grade ≥98%, High-Purity Grade ≥99%, Pharmaceutical Grade ≥99.5%
Molecular FormulaC22H24ClFN4O3
Molecular Weight446.9
Appearancewhite to off-white crystalline powder
Packaging1 kg/aluminum foil bag, 10 kg/fiber drum.
Testing IndicatorsAppearance — Visual inspection; Identification — IR, LC-MS; Purity — Gradient RP-HPLC; Polymorphic form — XRPD; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Filtration; Quinazoline dimers — SEC.
Storage NotesStored at -20°C in a tightly closed container under inert atmosphere, protected from light, oxygen, and moisture.
Lead Time
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days
Used as an EGFR tyrosine kinase inhibitor intermediate in the synthesis of oral first-line therapies for non-small cell lung cancer with EGFR mutations.