Acalabrutinib
CAS: 1420477-60-6
Category: Pyrazolone
| Purity | Reagent Grade ≥98%, High-Purity Grade ≥99%, Technical Grade ≥95% |
| Molecular Formula | C26H23N7O2 |
| Molecular Weight | 465.51 |
| Appearance | White to pale yellow crystalline powder |
| Packaging | 1 g/amber glass vial, 5 g/plastic bottle. |
| Testing Indicators | Appearance — Visual inspection; Identification — IR, LC-MS; Purity — Gradient RP-HPLC; Polymorphic form — XRPD; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Pour plate; BTK inhibitor impurities — SEC. |
| Storage Notes | Stored at -20°C in a tightly closed container under inert atmosphere, protected from light, moisture, and heat. |
| Lead Time | Deprecated: htmlspecialchars(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.demeichem.com/config/helpers.php on line 28 days |
Used as a second-generation BTK inhibitor intermediate in the synthesis of oral therapies for mantle cell lymphoma and chronic lymphocytic leukemia.