Abemaciclib (methanesulfonate)
CAS: 1231930-82-7
Category: Pyrazolone
| Purity | Reagent Grade ≥98%, High-Purity Grade ≥99%, Technical Grade ≥95% |
| Molecular Formula | C28H36F2N8O3S |
| Molecular Weight | 602.7 |
| Appearance | White to off-white crystalline powder |
| Packaging | 1g/5g/10g or 25kg/cardboard drum or 1kg/aluminum foil bag |
| Testing Indicators | Appearance — Visual inspection; Identification — IR, Methanesulfonate test; Purity — RP-HPLC; Methanesulfonate — Titration; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Filtration; CDK4/6 impurities — LC-MS. |
| Storage Notes | Stored in a cool, dry, and well-ventilated place in a tightly closed container, protected from light and moisture, away from incompatible materials, heat, and direct sunlight. |
| Lead Time | Deprecated: htmlspecialchars(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.demeichem.com/config/helpers.php on line 28 days |
Used as a potent and selective CDK4/6 inhibitor in the synthesis of antineoplastic agents for treating hormone receptor-positive, HER2-negative advanced or metastatic breast cancer and other solid tumors.