Nalfurafine (hydrochloride)

CAS: 152658-17-8

Category: Quinoline

PurityReagent Grade ≥98%, High-Purity Grade ≥99%, Technical Grade ≥95%
Molecular FormulaC28H33ClN2O5
Molecular Weight513.03
AppearanceWhite to off-white crystalline powder
Packaging1 g/amber glass vial, 5 g/plastic bottle.
Testing IndicatorsAppearance — Visual inspection; Identification — IR, Chloride test; Purity — Gradient RP-HPLC; pH — Potentiometry; Chloride — Argentometric titration; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Membrane filtration; Morphinan impurities — SEC.
Storage NotesStored at -20°C in a tightly closed container under inert atmosphere, protected from light and humidity.
Lead Time
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days
Used as a κ-opioid receptor agonist intermediate in the synthesis of oral antipruritic agents for uremic pruritus in hemodialysis patients.