Sonidegib

CAS: 956697-53-3

Category: Quinoline

PurityReagent Grade ≥98%, High-Purity Grade ≥99%, Technical Grade ≥95%
Molecular FormulaC26H26F3N3O3
Molecular Weight485.5
AppearanceWhite to pale yellow crystalline powder
Packaging1g/5g/10g or 25kg/cardboard drum or 1kg/aluminum foil bag
Testing IndicatorsAppearance — Visual inspection; Identification — IR, HPLC; Purity — RP-HPLC; Polymorphic form — XRPD; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Pour plate; Benzimidazole impurities — LC-MS.
Storage NotesStored in a cool, dry, and well-ventilated place below 30°C in a tightly closed container, protected from moisture and light, away from incompatible materials, heat, and direct sunlight.
Lead Time
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days
Used as a smoothened (Smo) antagonist in the hedgehog signaling pathway for synthesizing targeted therapies against locally advanced basal cell carcinoma.