153-18-4 | Rutin

Chemical type

• Flavonoid

^[1]

• Flavonoid glycoside

^[2]

Key properties

• Antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Acinetobacter baumannii
• Interferes with bacterial cell membranes, causing release of intracellular proteins and nucleic acids
• Reduces biofilm biomass by decreasing cell viability, exopolysaccharide, and extracellular DNA levels
• Potentiates antibacterial activity of antibiotics against methicillin-resistant Staphylococcus aureus (MRSA) strains
• Antioxidant activity
• Low water solubility (0.125 mg/mL) and poor bioavailability
• Anticancer and anti-inflammatory effects

^[1]

• Composed of quercetin and rutinose
• Free radical scavenging capacity
• Metal-chelating capacity
• Binds to proteins via static quenching, primarily through hydrophobic interactions
• Exhibits a concentration-dependent dual role (antioxidant at low/moderate levels, pro-oxidant at high levels)

^[2]

• Therapeutic agent for ocular infections such as conjunctivitis, keratitis, endophthalmitis
• Potentiator of antibiotic efficacy against resistant bacterial strains
• Component in inclusion complexes to improve solubility for drug delivery

^[1]

• Mitigates myofibrillar protein (MP) oxidation induced by heat and linoleic acid
• Reduces carbonyl formation in oxidized MP
• Maintains protein structural stability (e.g., higher α-helix proportion)
• Enhances gel properties (strength, elasticity, water-holding capacity) at optimal concentrations (20-40 μmol g⁻¹ protein)
• Competes with linoleic acid for binding sites on myosin, preferentially binding with higher affinity

^[2]

Classification by use

• Antibacterial agents
• Antibiofilm agents
• Antioxidants
• Anticancer and anti-inflammatory compounds

^[1]

• Natural antioxidant for food protein protection
• Functional food ingredient (gel quality enhancer)

^[2]

A trustworthy factory and manufacturer

Demei Chemical Technology Co., Ltd. is a modern high-tech enterprise integrating R&D, production, and sales. The company's founder, Dr. Arron, born in April 1975, graduated from the School of Mechanical Engineering at Yanshan University and has been engaged in research in the fields of mechanical engineering and chemical synthesis for many years. The company's products focus on the chemical industry, primarily dealing in chemical raw materials and chemical production machinery and equipment. With its strong technical capabilities, advanced production equipment, and strict quality management system, the company has earned the trust of customers worldwide.

1. [Cite:2] Rutin/Sulfobutylether-β-Cyclodextrin as a Promising Therapeutic Formulation for Ocular Infection, Pharmaceutics, 2024, 16(2), 233
2. [Cite:2] Mechanisms of rutin-mediated protection of grass carp myofibrillar protein under combined heat and linoleic-acid oxidation, LWT, Volume 242, 15 February 2026, 119155