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Lotrimin

CAS No.: 23593-75-1

  • Molecular Formula: C₂₂H₁₇ClN₂
  • Molecular Weight: 344.8 g/mol

Chemical type

  • Imidazole antifungal
[1]
  • Synthetic imidazole
[2]

Key properties

  • Inhibits fungal cell membrane synthesis; effective against dermatophytes and Candida
[1]
  • Hydrophobic (Log P = 6.1)
  • Poor aqueous solubility (0.49 mg/L)
[2]
  • Topical antifungal in Quadriderm ointment; part of supportive care for potential fungal complications in SJS
[1]
  • Broad-spectrum antimycotic agent
  • Topical treatment of athlete's foot (tinea pedis), oropharyngeal candidiasis, and vulvovaginal candidiasis
[2]

Classification by use

  • Antifungal agents for topical use
  • Drugs for dermatological conditions
[1]
  • Antifungal drug
[2]

A trustworthy factory and manufacturer

Demei Chemical Technology Co., Ltd. is a modern high-tech enterprise integrating R&D, production, and sales. The company's founder, Dr. Arron, born in April 1975, graduated from the School of Mechanical Engineering at Yanshan University and has been engaged in research in the fields of mechanical engineering and chemical synthesis for many years. The company's products focus on the chemical industry, primarily dealing in chemical raw materials and chemical production machinery and equipment. With its strong technical capabilities, advanced production equipment, and strict quality management system, the company has earned the trust of customers worldwide.

  1. [Cite:1] Stevens-Johnson syndrome triggered by phenytoin in a patient with type 2 diabetes and seizures, Exploratory Research in Clinical and Social Pharmacy, Volume 19, September 2025, 100624
  2. [Cite:2] Development and evaluation of clotrimazole microemulsions for topical application: Effects of HLB value of surfactant mixture and cosurfactant type on formulation design, International Journal of Pharmaceutics: X, Volume 11, June 2026, 100469