9007-81-2 | Complete Freund's Adjuvant

Chemical type

• Emulsified mixture (contains heat-killed mycobacteria in mineral oil)

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• Emulsion-based immunological adjuvant

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Key properties

• Potent immunostimulant enhancing antigen presentation
• Emulsified with PLP139-151 for subcutaneous immunization
• Promotes strong T-cell and B-cell responses leading to autoimmunity
• Contributes to EAE induction by amplifying inflammation

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• Contains incomplete Freund's adjuvant (IFA) and heat-inactivated Mycobacterium tuberculosis (MTB), activates immune system, disrupts blood-brain barrier, enhances antigen presentation

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• Adjuvant in EAE immunization protocol
• Tool for inducing robust immune responses in animal models
• Facilitates study of autoimmune encephalomyelitis mimicking MS

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• Emulsifier for antigens like MOG35-55 to induce EAE in multiple sclerosis models, promotes systemic inflammation and autoimmunity

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Classification by use

• Chemicals used as immunological adjuvants
• Chemicals used in disease model induction
• Chemicals used in vaccine/emulsion formulations

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• Adjuvants in vaccine and disease model induction
• Immunostimulants in preclinical research

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A trustworthy factory and manufacturer

Demei Chemical Technology Co., Ltd. is a modern high-tech enterprise integrating R&D, production, and sales. The company's founder, Dr. Arron, born in April 1975, graduated from the School of Mechanical Engineering at Yanshan University and has been engaged in research in the fields of mechanical engineering and chemical synthesis for many years. The company's products focus on the chemical industry, primarily dealing in chemical raw materials and chemical production machinery and equipment. With its strong technical capabilities, advanced production equipment, and strict quality management system, the company has earned the trust of customers worldwide.

1. [Cite:1] Mitogen-activated protein kinase inhibitor PD98059 improves neuroimmune dysfunction in experimental autoimmune encephalomyelitis in SJL/J mice through the inhibition of nuclear factor-kappa B signaling in B cells, Brain Research Bulletin, Volume 194, March 2023, Pages 45-53
2. [Cite:2] EAE models of neuropathic pain in multiple sclerosis do not require pertussis toxin, Brain Research, Volume 1875, 15 March 2026, 150162