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Poly(ethylene glycol)

CAS No.: 25322-68-3

  • Molecular Formula: -
  • Molecular Weight: - g/mol

Chemical type

  • Osmotic stress–inducing polymer
  • Water-soluble polyether
[1]
  • Polyether compound
  • Hydrophilic polymer
[2]

Key properties

  • High molecular weight, non-ionic polymer
  • Does not readily penetrate plant cell membranes
  • Creates osmotic pressure without ionic toxicity
  • Chemically inert and biologically stable
[1]
  • Biocompatible
  • Reduces cytotoxicity of cationic carriers
  • Enhances circulation time
  • Provides stealth effect against immune recognition
[2]
  • Induction of controlled osmotic (water-deficit) stress in plants
  • Mimics drought-like conditions without introducing ions
  • Comparative stressor against ionic stress (NaCl)
[1]
  • PEGylation of PEI to reduce toxicity
  • Improves stability and biodistribution of nanoparticles
  • Used in hybrid carriers (e.g., PEI-PEG-PCL)
[2]

Classification by use

  • Chemicals used to induce osmotic stress
  • Chemicals used in plant physiology experiments
  • Chemicals used as abiotic stress simulators
[1]
  • Polymers used for biocompatibility enhancement
  • Polymers used in stealth nanoparticle design
[2]

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  1. [1] Ca2+ and ROS signalling exhibit divergent root-specific dynamics in Arabidopsis responses to abiotic stress and PAMPs, Current Plant Biology, Volume 45, January 2026, 100571
  2. [2] Polyethylenimine Carriers for Drug and Gene Delivery, Polymers, 2025, 17(15), 2150