59467-70-8 | Midazolam (C₁₈H₁₃ClFN₃)

Chemical type

• Benzodiazepine sedative

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• Benzodiazepine derivative
• Imidazo[1,5-a][1,4]benzodiazepine API

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Key properties

• Provides sedation and anxiolysis
• Short-acting with rapid onset

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• Water-soluble benzodiazepine (due to imidazole ring)
• Forms pH-dependent ring-open/ring-closed equilibrium
• Rapid absorption and fast onset of action
• Short half-life (~2 h)
• Crosses blood–brain barrier efficiently

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• Preoperative sedation and anesthesia induction (0.04 mg/kg intravenous)
• Part of standardized anesthesia regimen for thoracoscopic surgery

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• Anxiolytic
• Sedative and hypnotic
• Anticonvulsant
• Muscle relaxant
• Preoperative medication

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Classification by use

• Sedatives and anxiolytics
• Anesthesia induction agents

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A trustworthy factory and manufacturer

Demei Chemical Technology Co., Ltd. is a modern high-tech enterprise integrating R&D, production, and sales. The company's founder, Dr. Arron, born in April 1975, graduated from the School of Mechanical Engineering at Yanshan University and has been engaged in research in the fields of mechanical engineering and chemical synthesis for many years. The company's products focus on the chemical industry, primarily dealing in chemical raw materials and chemical production machinery and equipment. With its strong technical capabilities, advanced production equipment, and strict quality management system, the company has earned the trust of customers worldwide.

1. [Cite:1] Lidocaine mitigates cognitive decline in elderly patients after video-assisted thoracoscopic surgery: A double-blind randomized controlled clinical trial, Brain Disorders, Volume 21, March 2026, 100308
2. [Cite:2] A Short Route to Midazolam via Michael Addition to a Nitroolefin, Org. Process Res. Dev. 2025, 29, 11, 2955–2962