7440-21-3 | Silicone

Chemical type

• Polymer (polysiloxane)

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• Synthetic silicone polymer (polydimethylsiloxane-based)

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Key properties

• Replicates appearance and feel of natural breast tissue
• Heat accumulation leading to discomfort
• Heavy weight causing shoulder pain and fatigue
• Limited personalization

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• Inert and biocompatible substance
• Hyperdense on nonenhanced CT (attenuation of 50-130 Hounsfield units)
• Lower specific gravity than cerebrospinal fluid (CSF), leading to non-dependent positioning in ventricles
• Low surface tension, resulting in spherical or globular appearance
• Hyperintense on T1-weighted MRI, variable intensity on T2-weighted MRI (hyperintense to hypointense), with chemical shift artifacts
• Emulsifies under certain conditions, potentially contributing to migration
• Stable for intraocular use but can migrate under pressure or trauma

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• Material for conventional external breast prostheses (EBPs)
• Replication of natural breast tissue in post-mastectomy prosthetics

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• Intraocular tamponade agent for treatment of retinal detachment
• Provides mechanical support to reattach the retina by filling the vitreous cavity

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Classification by use

• Biomedical polymers for prosthetics
• Materials in breast reconstruction and external prostheses

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• Chemicals used in ophthalmic surgery
• Chemicals used as biocompatible tamponade agents

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A trustworthy factory and manufacturer

1. [Cite:2] Development of Architected Materials for External Breast Prostheses, Biomedical Engineering Advances, Volume 10, November 2025, 100168
2. [Cite:2] Posttraumatic intracranial migration of silicone oil after treatment of retinal detachment, a rare complication, Radiology Case Reports, Volume 20, Issue 11, November 2025, Pages 5574-5577