2-Methylbenzofuro[2,3-b]pyridin-8-yl trifluoromethanesulfonate
CAS: 1609373-98-9
Category: Organic Pharmaceutical Intermediates
| Purity | ≥97.0% (HPLC); ≥98.0% (HPLC); ≥99.0% (HPLC) |
| Molecular Formula | C13H8F3NO4S |
| Molecular Weight | 331.27 |
| Appearance | Off-white to pale yellow crystalline powder |
| Packaging | 100 mg, 250 mg, 1 g, 5 g, 10 g, 25 g, or 100 g amber glass bottle or aluminum foil bag with moisture-proof inner liner |
| Testing Indicators | Appearance — Visual inspection; Identification — LC-MS, HRMS, FTIR, 1H NMR, 13C NMR and 19F NMR; Assay/Purity — HPLC (UV); Related substances — HPLC; Water content — Karl Fischer titration (USP <921>); Residual solvents — GC (USP <467>); Melting point — USP <741>; Elemental impurities — ICP-MS/ICP-OES; Structure confirmation — High-resolution mass spectrometry and NMR spectroscopy. |
| Storage Notes | Store tightly sealed in a cool, dry, well-ventilated area. Protect from moisture, light, and heat. Recommended long-term storage at 2–8°C under nitrogen or argon. Open containers only under dry conditions and reseal immediately after use. |
| Lead Time | 10 days |
A heteroaryl triflate used as an advanced pharmaceutical intermediate in medicinal chemistry. Serves as an excellent electrophilic substrate for Suzuki-Miyaura, Buchwald-Hartwig, Negishi, Stille, Kumada, and Sonogashira cross-coupling reactions to synthesize heterocyclic drug candidates, kinase inhibitors, and functional organic materials.